GHRP-2
Status
No approved product. No FDA-approved labeling exists. GHRP-2 is not an approved medicine in the United States, though it has been used as a diagnostic agent in other countries.
What it is
An older GH releasing peptide with strong appetite and prolactin signal.
What published research measured
A synthetic hexapeptide that acts on the ghrelin receptor to trigger growth hormone release from the pituitary. Human pharmacology is reasonably well described because it was studied as a diagnostic agent for growth hormone deficiency: it produces a reliable, dose-related GH pulse in healthy adults and in deficient patients. What is not established is any trial evidence for the reasons it is actually used outside medicine — body composition or performance in healthy adults. Published human work consistently notes that the GH rise does not come alone: modest increases in prolactin and cortisol are reported alongside it, which distinguishes this peptide from the more selective secretagogues.
Source
Frontiers in Endocrinology 2026 review — GH secretagogues and the GH–IGF-1 axis
Sources
No linked primary source is on file for this entry yet.
Educational use only, never medical advice. No doses.